Musculoskeletal clinical research studies
Musculoskeletal disorders affect the muscles, joints, tendons, ligaments and bones of the body and affect people of all ages. Conditions such as
Osteoarthritis, and Rheumatoid Arthritis cause pain, disability, and depression. We are conducting important clinical research to help improve care and treatment for our patients.
Your NHS trust hospital supports 12 clinical studies on musculoskeletal
conditions that are currently recruiting participants:
1. Adjacent Segment Disc Degeneration (ASDD) multicentre study
Long term follow up (>10 years) of patients with chronic low back pain from 3 trials comparing fusion and non-operative care. Is Adjacent
Segment Disc Degeneration (ASDD) more likely in
patients treated
with fusion?
2. BRAGGS Study
Investigation of genes influencing
response to treatment with Infliximab, 
Etanercept and Adalumimab in patients
with rheumatoid arthritis and
related arthropathies
Summary
There are two parts to the study: The Cross Sectional Arm - for patients on an anti TNF drug and registered on the BSRBR. One single blood sample required for DNA testing. The Prospective Arm - for new patients about to start an anti TNF drug. We will be collecting the clinical, serological, psychological and genetic data in place of the BSRBR.
- Contact study coordinator Mary Brown on 0208 568123 or e-mail
- NIHR CRN Portfolio
- Study website
- Patient Information Sheet
3. TABUL study
The role of ultrasound compared to biopsy of temporal arteries in the
diagnosis and treatment of giant cell arteritis (TABUL).
Summary
(No Summary on NIHR portfolio)
- Contact study coordinator Dr Surjeet Singh on 01865 227326 or e-mail
- Study website
- NIHR CRN Portfolio
4. TRACE RA study
5. AIM: Ankle Injury study
6. CSAW: Shoulder pain study
7. KAT: Knee study
8. TOPKAT: Knee study (Total or Partial knee Arthroplasty)
9. Rotator cuff tear study
10. Osteoarthritis study
11. Lupus study
12. Ankylosing Spondylitis study